Fat Metabolism
Fat, or lipid, metabolism consists of several processes.
Catabolism (breakdown) of lipids for energy involves the hydrolysis of
triglycerides into two-carbon units that become part of acetyl coenzyme A
(acetyl CoA). The acetyl CoA then enters the series of reactions called the TCA
cycle, eventually leading to the oxidation of the carbon and hydrogen atoms
derived from fatty acids (or carbohydrates or amino acids) to carbon dioxide and
water with the release of energy as adenosine triphosphate (ATP). If fat
catabolizes quickly because of a lack of carbohydrate for energy, the liver
cells form intermediate products called ketone bodies. These ketone bodies
accumulate in the blood, causing a condition called ketosis. | |||||||||||||||
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